Intraoperative management of phaeochromocytoma with sodium nitroprusside.
نویسندگان
چکیده
منابع مشابه
Deliberately Lowering Blood Pressure with Sodium Nitroprusside
The goal of hyptensive anesthesia is the safe reduction of intraoperative blood loss, thus reducing transfusion risks. Previous hypotensive technics had a narrow margin of safety in that cardiac output was usually reduced in proportion to the degree of induced hypotension. This is in contrast to the results of our study, in which Sodium Nitroprusside was used as the sole hypotensive agent. Ni...
متن کاملSodium nitroprusside is not associated with metabolic acidosis during intraoperative infusion in children
BACKGROUND Sodium nitroprusside (SNP) is a potent vasodilator that has been used to induce deliberate hypotension in children during surgery involving significant blood loss, including craniofacial and spinal fusion procedures. SNP metabolism liberates cyanide, which may cause interference with cellular energy metabolism, leading to metabolic acidosis and central nervous system injury. We perfo...
متن کاملSodium Nitroprusside Injection
Except when used briefly or at low (< 2 mcg/kg/min) infus ion rates , sodium nitropruss ide gives rise to important quantities of cyanide ion, which can reach toxic, potentially lethal levels (see WARNINGS). The usual dose rate is 0.5 to 10 mcg/kg/min, but infus ion at the maximum dose rate should never las t more than 10 minutes . If blood pressure has not been adequately controlled after 10 m...
متن کاملSodium nitroprusside: theory and practice.
Sodium nitroprusside, by a peripheral vasodilator action, is a powerful hypotensive drug. In contrast to established agents, its hypotensive action is accompanied by an unchanged or augmented cardiac output. Intravenous administration of sodium nitroprusside rapidly produces a profound and controllable hypotension. Normotension is swiftly restored by ceasing to infuse the agent, and antidotes a...
متن کاملAnaesthetic management of patients with phaeochromocytoma.
The presence of a phaeochromocytoma is a hazardous and dramatic cause of arterial hypertension accounting for approximately fewer than 0.1% of all cases of hypertension (Manger and Gifford, 1977). Phaeochromocytomas are functionally active, catecholamine-containing tumours of chromaffin tissue, found usually in the adrenal medulla, but they may occur at any site where chromaffin tissue is locat...
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ژورنال
عنوان ژورنال: BMJ
سال: 1978
ISSN: 0959-8138,1468-5833
DOI: 10.1136/bmj.2.6144.1088